In chronic inflammatory and autoimmune diseases such as fibromyalgia, ulcerative colitis, or Hashimoto’s thyroiditis, the immune system attacks its own tissues and is overstimulated. Metal-based bridges, amalgam fillings, and metal-fastening dentures that remain in the mouth for years undergo continuous micro-corrosion, releasing heavy metals and foreign ions into the body. The immune system constantly produces cytokines (inflammatory chemicals) to eliminate these ions, which continuously fuels the systemic inflammation load. When all metals in these patients’ mouths are removed using the SMART protocol and replaced with 100% biocompatible ceramic structures, this “constant alarm” load on the immune system is eliminated. Clinically, patients can observe significant reductions in fibromyalgia muscle pain, improvements in intestinal mucosa, and decreases in autoimmune antibody levels.